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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYO7A All Species: 16.97
Human Site: S677 Identified Species: 37.33
UniProt: Q13402 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13402 NP_000251.3 2215 254406 S677 A G Y P I R Y S F V E F V E R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087868 2196 251859 S708 A G Y P I R Y S F V E F V E R
Dog Lupus familis XP_542292 2172 250204 S674 A G Y P I R Y S F V E F V E R
Cat Felis silvestris
Mouse Mus musculus P97479 2215 254831 S677 A G Y P I R Y S F V E F G E R
Rat Rattus norvegicus Q9QYF3 1828 211745 K410 L A K H I Y A K L F N W I V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q02440 1829 212364 L411 A K H I Y A N L F N W I V D H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A5PF48 1026 118045
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3Z6 2167 250290 G671 A G Y P I R H G F R E F V E R
Honey Bee Apis mellifera XP_001122406 2102 243763 S654 C C R Q L R Y S G M M E T I R
Nematode Worm Caenorhab. elegans P91443 2098 239766 S650 V L R Q L R Y S G M M E T I K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19524 1574 180662 Q156 R L M K N D K Q N Q T I V V S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.6 95.5 N.A. 96.4 23.8 N.A. N.A. 24.2 N.A. 21.8 N.A. 61.7 61.5 50.5 N.A.
Protein Similarity: 100 N.A. 96.3 97.1 N.A. 98.5 41.1 N.A. N.A. 41.7 N.A. 31 N.A. 76.9 76.1 67.4 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 6.6 N.A. N.A. 20 N.A. 0 N.A. 80 26.6 20 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 20 N.A. N.A. 33.3 N.A. 0 N.A. 86.6 40 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 10 0 0 0 10 10 0 0 0 0 0 0 0 0 % A
% Cys: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 46 19 0 46 0 % E
% Phe: 0 0 0 0 0 0 0 0 55 10 0 46 0 0 0 % F
% Gly: 0 46 0 0 0 0 0 10 19 0 0 0 10 0 10 % G
% His: 0 0 10 10 0 0 10 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 10 55 0 0 0 0 0 0 19 10 19 0 % I
% Lys: 0 10 10 10 0 0 10 10 0 0 0 0 0 0 10 % K
% Leu: 10 19 0 0 19 0 0 10 10 0 0 0 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 19 19 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 10 0 10 10 10 0 0 0 0 % N
% Pro: 0 0 0 46 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 19 0 0 0 10 0 10 0 0 0 0 0 % Q
% Arg: 10 0 19 0 0 64 0 0 0 10 0 0 0 0 55 % R
% Ser: 0 0 0 0 0 0 0 55 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 19 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 37 0 0 55 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % W
% Tyr: 0 0 46 0 10 10 55 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _